Abstract: Objective： To investigate the recurrence status in patients with bone metastasis within 6 months after operation, and analyze the risk factors for recurrence. Methods： A total of 689 patients undergoing surgical operation on bone metastasis were selected. And the patients were divided into 2 groups according to results of 6 months’ follow-up. The 64 patients with metastasis recurrence within 6 months were recurrence group, and the other 625 patients were non-recurrence group. Patients’ general data were recorded in two groups, and the risk factors for tumor recurrence in situ within 6 months after operation were analyzed. Results： Poor preoperative general condition, primary tumor with rapid progress, lesion associated with axial skeleton, preoperative local radiotherapy, receiving a systemic therapy before operation, and lack of systemic therapy after operation, were risk factors for tumor recurrence in situ (P< 0.05). Conclusions： The operation method should be chosen carefully for patients with poor preoperative general condition or rapid tumor progress, tumor in axial sketeton, receiving systemic therapy before operation or preoperative local radiotherapy. Patients with bone metastasis should receive systemic treatment after operation, to consolidate the efficacy of operation.