不同代320排螺旋CT机全肝灌注成像辐射剂量及灌注参数的比较

申晓俊; 吴东; 汤敏; 陈财忠; 金航; 曾蒙苏

不同代320排螺旋CT机全肝灌注成像辐射剂量及灌注参数的比较

申晓俊^1,2,3,
吴东^1,2,3,,
汤敏^1,2,3,
陈财忠^1,2,3,
金航^1,2,3,
曾蒙苏^1,2,3

1.
复旦大学附属中山医院放射科，上海 200032
2.
上海市影像医学研究所，上海 200032
3.
复旦大学上海医学院影像系，上海 200032

基金项目: 上海市卫生和计划生育委员会课题(201540142）

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出版历程
- 刊出日期: 2018-12-24

Comparison of the radiation dose and perfusion parameters of whole liver computed tomography perfusion with different generations of 320-detector computed tomography

摘要

摘要: 目的：回顾性分析第1代320排螺旋CT机和第2代320排螺旋CT机全肝CT灌注成像（CTPI）辐射剂量的差异及对灌注参数的影响。方法：随机抽取行全肝CTPI的78例患者的影像学资料，其中采用第1代320排螺旋CT机者42例（第1代组），第2代320排螺旋CT机者36例（第2代组）。比较两组间正常肝脏实质的灌注参数，包括肝动脉血流量（hepatic arterial flow，HAF）、门静脉血流量（portal venous flow，PVF）及灌注指数（perfusion index，PI）。比较两组辐射剂量，包括容积CT剂量指数（volume CT dose index，CTDIvol）、剂量长度乘积（dose length product，DLP）和有效辐射剂量（effective radiation dose，ED）。结果：两组灌注参数HAF、PVF及PI值差异无统计学意义。第2代组辐射剂量参数（CTDIvol、DLP、ED）值较第1代组明显减小（P<0.01），减小幅度均约46%。结论：第2代320排螺旋CT机能降低全肝CTPI的辐射剂量，同时对灌注参数值无显著影响。
- 计算机断层扫描 /
- 辐射剂量 /
- 肝脏 /
- 灌注成像
Abstract: Objective：To retrospectively analyze the differences of radiation dose and perfusion parameters of whole liver computed tomography (CT) perfusion using the first and second-generation 320-detector CT machine. Methods：Imaging data of 78 randomly enrolled patients who underwent whole liver CT perfusion were analyzed. Among which, 42 patients (group A) were examined with the first-generation 320-detector CT, while 36 patients (group B) were examined with the second-generation CT. The CT perfusion parameters of normal liver tissue including the hepatic arterial flow (HAF), the portal venous flow (PVF), the perfusion index (PI) were compared between the two groups. And the radiation dose parameters including the volume CT dose index (CTDI), the dose length product (DLP), and the effective radiation dose (ED) were compared between the two groups. Results：No significant difference in the perfusion parameters (HAF, PVF, and PI) was found between the two groups. The radiation dose (CTD, DLP, and ED) in group B reduced obviously than that in group A (P<0.01). Conclusions：The second-generation 320-detector CT has reduced radiation dose for the whole liver CT perfusion, and does not significantly affect the perfusion parameters.
- computed tomography /
- radiation dose /
- liver /
- perfusion imaging