Abstract: Objective：To investigate the clinical effect and adverse reactions of subcutaneous implantation contraception for women of childbearing age, and provide evidence support for contraceptive efficacy of subcutaneous implantation. Methods：A total of 200 women of childbearing age who accepted subcutaneous implantation contraception in our hospital between January 2015 and June 2016 were included in the study. A telephone follow-up was conducted every 90 days to record the contraceptive effect and adverse reactions. Results：The success rate of subcutaneous implantation contraception was 95.2%. Forty-five adverse reactions were recorded during the follow-up period, with a incidence of 24.1%. The most common adverse reaction was abnormal bleeding (64.4%), followed by early pregnancy reaction (13.3%). Bleeding reduction was the most common type of abnormal bleeding (11/29). Conclusions：The clinical contraceptive effect of subcutaneous implantation is acceptable, and it is suitable for popularization and use under the condition of reasonable control of its adverse reactions.