低热卡肠外营养对老年胃癌患者术后恢复的影响
Effect of Hypocaloric Parenteral Nutrition on Postoperative Recovery in Aged Patients with Gastric Cancer
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摘要: 目的: 观察低热量肠外营养(PN)治疗对老年胃癌患者术后恢复的影响。 方法: 60例老年胃癌患者按术后PN供给热量的不同分为观察组和对照组,每组30例。观察组采用低热量PN,热量为18 kcal/kg/d,含氮量为0.1 g/kg/d;对照组热量为30 kcal/kg/d,含氮量为0.2 g/kg/d,两组均连续6 d。比较两组血清C反应蛋白(CRP)、血清蛋白、血糖、感染性并发症及住院时间等指标的差异。 结果: 观察组第6天血清CRP水平较对照组下降,血清前白蛋白、转铁蛋白水平较对照组增加(P<0.05)。两组术后血糖浓度无明显差异,但观察组术后第6天胰岛素用量明显少于对照组(P<0.05),且感染性并发症减少、住院时间缩短(P<0.05)。结论: 低热量PN治疗有助于促进老年胃癌患者的术后康复。Abstract: Objective: To observe the effect of hypocaloric parenteral nutrition(PN) regimen on the postoperative recovery in aged patients with gastric cancer. Methods: Sixty aged patients with gastric cancer were divided into observation group (n=30) and control group (n=30) on the basis of postoperative PN feeding strategies.The observation group received hypocaloric PN which contained calorie 18 kcal/kg/d and nitrogen 0.1 g/kg/d. And the control group received calorie 30 kcal/kg/d and nitrogen 0.2 g/kg/d. Both groups have been provided with PN for 6 days continuously .The differences regarding C-reactive protein(CRP), serum albumin, blood glucose, infectious complications and duration of hospital stay were compared between the two groups. Results: CRP level on the 6th day in observation group was significantly lower than that in control group, while levels of serum prealbumin and transferrin in observation group were higher than those in control group (P<0.05). There was no significant difference regarding blood glucose concentration between the groups, but the dose of insulin administered on the 6th day in observation group was significantly lower than that in control group (P<0.05). And both infectious complications and duration of hospital stay in observation group were fewer than those in control group (P<0.05). Conclusions: Hypocaloric PN regimen was conducive to postoperative recovery in aged patients with gastric cancer.