基于三维真实重建反转恢复序列成像分析年龄与梅尼埃病患者内淋巴积水发生的关系

陈伟; 沙炎; 程卫玲

doi:10.12025/j.issn.1008-6358.2025.20241563

基于三维真实重建反转恢复序列成像分析年龄与梅尼埃病患者内淋巴积水发生的关系

Effect of age on endolymphatic hydrops in Meniere’s disease patients based on three-dimensional inversion-recovery with real reconstruction sequence imaging

摘要

摘要:
目的基于3D-real IR序列磁共振成像探讨梅尼埃病患者内耳内淋巴积水（endolymphatic hydrops, EH）的发生与年龄的相关性。
方法回顾性选择101例明确诊断为单侧梅尼埃病（Meniere’s disease, MD）的患者，按年龄分为青年组（＜18岁）、中年组（18～45岁）和老年组（＞45岁）。所有患者均在接受静脉注射钆对比剂4 h后，进行三维真实重建反转恢复（three-dimensional inversion-recovery with real reconstruction, 3D-real IR）MRI检查。比较不同年龄组EH发生率。
结果青年组、中年组和老年组的EH阳性率分别为68.2%（15/22）、54.5%（18/33）和56.5%（26/46），差异无统计学意义。不同年龄组前庭及耳蜗EH阳性率差异无统计学意义。不同年龄组前庭及耳蜗不同严重程度EH阳性率差异无统计学意义。
结论梅尼埃病患者年龄与内耳EH的发生无明显相关性。

Abstract:
Objective To analyze correlation of endolymphatic hydrops (EH) in the inner ear with age in Meniere’s disease (MD) patients.
Methods A retrospective analysis were underwent in 101 definite unilateral MD patients. They were divided into young-age (＜18 years old) group, middle-age (18-45 years old) group and elder-age (＞45 years old) group. All patients underwent inner ear three-dimensional inversion-recovery with real reconstruction (3D-real IR) imaging 4 hours after intravenous gadolinium injection. EH rates among different groups were compared.
Results The positive rates of EH in the young-age group, middle-age group and elder-age group were 68.2% (15/22), 54.5% (18/33) and 56.5% (26/46), respectively (P＝0.567). There was no difference in the positive rates of EH in vestibule and cochlea among three groups. There was no difference in the rates of mild and significant EH in vestibule and cochlea among three groups.
Conclusions Age might not be related to the occurrence of EH in the inner ear in MD patients.

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