Abstract:
Objective To investigate the safety and efficacy of interventional therapy in patients with secondary atrial septal defect (ASD) with complete aortic rim deficiency.
Methods 402 patients with ASD who underwent transcatheter closure and followed up in outpatient at both 6-month and 1-year in the Department of Cardiology, Zhongshan Hospital, Fudan University from January 2018 to June 2020 were enrolled. They were divided into complete aortic rim deficiency group and normal aortic rim group. The clinical features, interventional parameters, and complications were compared between the two groups. Echocardiographic were used to evaluate the outcome.
Results The occluder size was larger in the aortic rim deficiency group (26.4±6.9 mm, n=128) than that in normal aortic rim group (23.4±7.7 mm, P < 0.001; n=274). Both groups exhibited no major postoperative complications, and significant improvements were observed in right heart remodeling following the operation, including pulmonary artery pressure decreasing, the diameters of the right atrium and right ventricle reducing, and the degree of tricuspid regurgitation reducing (P < 0.001). There was no significant change in left ventricular ejection fraction in all patients.
Conclusion Transcatheter closure of ASD with complete aortic rim deficiency is safe and feasible.
下载: