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新生儿腹部实体肿瘤临床特征分析

Clinical characteristics of neonatal abdominal solid tumor

  • 摘要:
    目的 探讨新生儿腹部实体肿瘤的临床特征。
    方法 回顾性分析2011年9月至2021年9月郑州大学第一附属医院收治的31例新生儿腹部实体肿瘤患儿的病例资料,并进行随访。
    结果 31例患儿中男性17例,女性14例。产前超声检查发现腹部占位12例(38.7%),出生后发现腹部占位19例(61.3%)。恶性肿瘤13例,其中神经母细胞瘤7例,手术治疗后存活3例、自然消退1例、失访3例;肝母细胞瘤5例,手术治疗后存活1例、死亡2例、失访2例;恶性畸胎瘤1例,手术治疗后存活。良性肿瘤18例,其中肝血管瘤16例,手术治疗后存活4例、肿瘤自然消退1例、带瘤生存10例、失访1例;良性畸胎瘤2例,手术切除后未复发。
    结论 产前检查有助于早期发现部分实体肿瘤,根据肿瘤的性质不同,治疗方案不尽相同。早期、合理的治疗及严密随访对改善患儿预后有重要意义。

     

    Abstract:
    Objective To explore the clinical characteristics of neonatal abdominal solid tumor.
    Methods The case information of 31 newborns with abdominal solid tumors treated in the First Affiliated Hospital of Zhengzhou University from September 2011 to September 2021 were retrospectively analyzed and followed up.
    Results Among the 31 cases, there were 17 males and 14 females. Twelve cases (38.7%) were found by prenatal ultrasound, and 19 cases (61.3%) were found after birth. There were 13 cases of malignant tumors, including 7 cases of neuroblastoma (3 cases of survival, 1 case of spontaneous regression and 3 cases of loss to follow-up), 5 cases of hepatoblastoma (1 case of survival, 2 cases of death and 2 cases of loss to follow-up), and 1 case of malignant teratoma that survived after surgical treatment. There were 18 cases of benign tumor, including 16 cases of hepatic hemangioma (4 cases of survival after operation, 1 case of spontaneous regression, 10 cases of survival with tumors and 1 case of loss to follow-up) and 2 cases of benign teratoma that had no recurrence after surgical resection.
    Conclusions Prenatal examination is helpful to find some solid tumors in the early stage and the treatment plan is different according to the nature of the tumor. Early and reasonable treatment and close follow-up are of great significance to improve the prognosis of children.

     

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