Abstract: In recent years, the aging population structure has led to an increase in the number of diabetic patients, and more and more scholars are using the tibial transverse transport technique as an option to treat diabetic foot. The TTT technique is a surgical technique based on the principle of "tension-stress" effect, which transforms mechanical stimuli into biological signals to promote wound healing in diabetic foot ulcers by improving microcirculation. The technique improves the microcirculation through a number of biological mechanisms, such as skylight opening effect; promoting the secretion of cytokines; macrophage polarization balance reconstruction; and stem cell mobilization. Therefore, this paper will briefly review the principle and steps of the TTT technique, and its biological mechanism of improving foot microcirculation in diabetes.