Objective To explore the clinical effects of radical proximal gastrectomy with double tract digestive reconstruction in patients with Siewert Ⅱ-Ⅲ adenocarcinoma of esophagogastric junction.

Methods Through a retrospective research, 60 patients with Siewert Ⅱ-Ⅲ adenocarcinoma of esophagogastric junction of Affiliated Danyang Hospital of Nantong University from December, 2017 to March, 2020 were admitted. 30 patients who underwent radical proximal gastrectomy with double tract digestive reconstruction were admitted to the observation group, and the other 30 patients who underwent radical total gastrectomy with Roux-en-Y digestive tract reconstruction were admitted to the control group. Relevant indications of intraoperative, postoperative and follow-up data in the two groups were compared.

Results The difference was statistically significant in the total operation time, gastrointestinal reconstruction time and drain fluid amylase level obtained on the third day after surgery in the two groups (all P < 0.05). The difference of the intraoperative bleeding volume, lymph node dissection number, postoperative first out of bed time, postoperative first exhaust time, postoperative feeding time, postoperative complication rate and postoperative hospital stay was not statistically significant. The increase of the serum gastrin, hemoglobin, albumin, and body mass in the observation group was higher than that in the control group in the following 6 months, 12 months and 24 months after surgery, and the difference was statistically significant (all P < 0.05), but the difference between the single food intake and the symptoms of the digestive system after surgery (gastroesophageal reflux) was not statistically significant.

Conclusion The patients in the observation group can maintain the dual-channel physiological activity and digestive function after operation, and during the period of follow up, the patients in the observation group can maintain a good nutritional condition for a long time. The result of the study is safe and feasible, so it is worthy of popularization and application in clinic.