Abstract:
Objective To explore the optimal method and the medical reference range of liver shear wave elastography (SWE) and shear wave dispersion (SWD) imaging in healthy adults.
Methods From May to October 2020, 50 healthy people in Zhongshan Hospital, Fudan University were selected, the SWE and SWD data of the liver in 50 healthy subjects were collected. The influence of different measuring positions, different sampling areas, different ages or genders on the SWE and SWD values was analyzed, then the normal liver reference range of healthy adults was determined.
Results The success rate of the S5/S6 section of the right lobe of the liver was 100%, which was higher than that of the maximum section of the left lobe of the liver (76%). The internal consistency and dispersion degree of the measured values of the right lobe were also better than those of the left lobe of the liver. So the right anterior lobe of the liver was the best measuring position. There was no significant difference in SWE and SWD values among different sampling area (10 mm and 20 mm in diameter), age, or gender groups.
Conclusions SWE and SWD technology have a high success rate and good stability. The right anterior lobe of the liver is the best site for measuring. Different sampling areas, different gender, and ages have no influence on the measured value. According to our study, the normal range of SWE and SWD values of the liver in healthy adults were 3.93~8.75 kPa and 8.80~14.99 m/(s·MHz), respectively.
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