Abstract: Noninvasive myocardial work is a newly developed echocardiography technology. It combines two-dimensional speckle tracking imaging and noninvasive estimation of left ventricular pressure to obtain the work of each segment and the whole left ventricle from mitral valve closure to mitral valve opening. It can quantitatively, objectively, and sensitively evaluate the regional and global myocardial function, showing advantages in evaluating various cardiovascular diseases, and might have a great application prospect.