Abstract: Idiopathic membranous nephropathy is a kind of autoimmune disease. Its duration is long and it is easy to develop into end-stage renal disease. The precision pharmacy abandons the traditional non-individualized medication method and can provide patients with accurate, safe, and economical individualized medication scheme. This paper summarizes some technical means which are based on the precision pharmacy, such as therapeutic drug monitoring, pharmacogenomics and population pharmacokinetics in the treatment of idiopathic membranous nephropathy to provide reference for clinical rational drug use.