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老年住院患者低白蛋白血症临床特征分析

Characteristics and management strategies of hypoalbuminemia in elderly hospitalized patients

  • 摘要:
    目的 探讨老年住院患者低白蛋白血症的临床特征及处理策略。
    方法 选择140例老年低白蛋白血症患者,分析白蛋白水平与炎性因子相关性、治疗前后白蛋白水平变化、存活组和死亡组的影响因素。
    结果 白蛋白水平与血沉ESR(r=-0.228,P < 0.05)、C反应蛋白CRP(r=-0.339,P < 0.05)及纤维蛋白原FIB(r=-0.235,P < 0.05)负相关;死亡组患者白蛋白水平更低(P < 0.05)。给予营养支持或静脉补充白蛋白,患者白蛋白水平无明显提高。
    结论 老年低白蛋白血症发生率高,治疗应首先控制原发疾病,补充白蛋白效果有限,临床上应严格、合理应用白蛋白。

     

    Abstract:
    Objective To analyze the characteristics and management strategies of hypoalbuminemia in elderly hospitalized patients.
    Methods A total of 140 elderly patients with hypoalbuminemia were enrolled. The relationship between albumin levels and inflammatory factors, albumin levels before and after treatment, and the impact factors of survival group and death group were compared.
    Results Albumin levels were negatively correlated with erythrocyte sedimentation rate (r=-0.228, P < 0.05), C-reactive protein (r=-0.339, P < 0.05), and fibrinogen (r=-0.235, P < 0.05). Patients of death group had lower albumin levels.With nutritional support or intravenous albumin, there was no significant increase in albumin levels in patients.
    Conclusions The incidence of hypoalbuminemia in elderly patients is high. The first aim is to control the primary disease, and not to supplement albumin. It is necessary to apply albumin strictly and rationally.

     

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