水交换法肠镜检查中加入靛胭脂提高腺瘤检出率的对比研究

胡学军; 徐威; 姚平; 沈明; 钟晓峰; 邱全兴; 汤瑜; 花海兵

doi:10.12025/j.issn.1008-6358.2019.20191289

水交换法肠镜检查中加入靛胭脂提高腺瘤检出率的对比研究

Comparative study on increasing adenoma detection rate by adding indigo rouge in enteroscopy with water exchange method

摘要

摘要:
目的探讨水交换法中加入靛胭脂提高腺瘤检出率的有效性。
方法前瞻性入组病例，随机采用常规水交换法（对照组）或加用0.008%靛胭脂水交换法（试验组）进行结肠镜检查。研究评价的主要指标为腺瘤检出率。
结果共202例患者纳入研究，试验组和对照组各101例。两组性别分布、平均年龄、吸烟史、结肠癌家族史和肠镜检查适应证差异无统计学意义。两组盲肠插管成功率均为100%。对照组腺瘤检出率为31.7%，试验组腺瘤检出率为45.4%，两组差异有统计学意义（P < 0.05）。
结论加用0.008%靛胭脂的水交换法肠镜检查可显著提高腺瘤检出率。

Abstract:
Objective To evaluate the efficacy of increasing adenoma detection rate (ADR) by adding indigo rouge in enteroscopy with water exchange method.
Methods Patients were enrolled prospectively. Colonoscopy was performed with routine water exchange (control group) or with 0.008% indigo carmine added water exchange method (study group). The primary outcome of this study is ADR.
Results Totally, 202 patients were included (101 cases in each group). There were no significant differences in gender distribution, mean age, smoking history, family history of colon cancer, and colonoscopy indication. Cecal intubation success rate was 100% in both groups. ADR was 31.7% for control group and 45.4% for study group, with significant difference (P < 0.05).
Conclusions Adding 0.008% indigo rouge in enteroscopy with water exchange method enhances ADR significantly.

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