腹膜后软组织肉瘤预后因素及预测工具的研究进展

Research progress of prognostic factors and prediction tools for retroperitoneal soft tissue sarcomas

摘要: 腹膜后软组织肉瘤（retroperitoneal sarcoma，RPS）是一类少见的恶性肿瘤，但其病理类型复杂多样。随着对RPS认识的逐渐深入，临床发现组织学类型、TNM分期、手术范围、辅助治疗方式等均可不同程度地影响RPS患者预后。虽然目前有列线图能够预测部分RPS术后患者的总体生存（OS）及无病生存期（DFS），但价值有限且无法指导RPS患者术后治疗。因此，本文就RPS预后相关因素及预测工具作一述评。

Abstract: Retroperitoneal sarcomas (RPS) are rare malignant tumors, and their pathological types are complex and varied. With the insight of RPS, the histological types, TNM stage, surgical extension, and adjuvant therapy all affect the prognosis of RPS patients to different degrees.The current nomograms can partially predict the overall survival (OS) and disease-free survival (DFS) of RPS patients, but due to their limited value, they cannot guide the post-operative treatment of RPS patients. This review mainly focuses on the prognostic factors and prediction tools for RPS.