Abstract: Objective：To compare the clinical efficacy of Ilizarov external fixator combined with finite orthopedic surgery and pure Ilizarov technique in the treatment of adolescent Ⅲ degree talipes equinovarus deformity.Methods：According to different treatment method, 57 patients with Ⅲ degree talipes equinovarus deformity were divided into Ilizarov external fixator combined with finite orthopaedic surgery group (35 cases) and pure Ilizarov technique group (32 cases). After the operation, the patients received the physical examination, the therapeutic effect was evaluated according to the ICFSG rating criteria, and the incidence of complications such as postoperative infection, nerve vessel damage, and muscular imbalance were compared between the two groups.Results：The ICFSG scores of patients after therapy by Ilizarov external fixator combined with finite orthopedic surgery and pure Ilizarov technique were significantly lower than those before therapy(P<0.05).The optimal rate of postoperative foot recovery in the combined surgery group was 91.89%, which was significantly higher than that in the pure Ilizarov technique group (75.00%, P<0.05).The incidence rate of postoperative complications in the combined surgery group was 8.11%, which was lower than that in pure Ilizarov technique group (18.75%, P<0.05).Conclusions：As compared with pure Ilizarov technique, the Ilizarov external fixator combined with finite orthopedic surgery can effectively improve the optimal rate of postoperative foot recovery for the adolescent patients with Ⅲ degree talipes equinovarus deformity, and significantly reduce the incidence of postoperative complications, worthy of clinical popularization and application.