Abstract: Objective：To investigate the effect of allinone medical nursing care on adolescent with scoliosis surgery. Methods：Totally 60 adolescent scoliosis patients were selected and randomly divided into interventional group and control group. The control group received routine nursing, while interventional group received allinone medical nursing care. Wakeup quality, wakeup time in operation, postoperative body temperature and extubation time were compared in two groups. Zung self rating anxiety scale (SAS), Zung self rating depression scale (SDS) were compared. Results：Wakeup time and extubation time in the interventional group were significantly less than those in the control group(P<0.05),wakeup quality and postoperative body temperature were significantly higher than those in the control group(P<0.05).SAS and SDS scores in the interventional group were significantly lower than those in the control group(P<0.05). Conclusions：Allinone medical nursing care could effectively improve wakeup quality, protect the body temperature, reduce extubation time and improve the negative emotions in patients with adolescent scoliosis surgery.