Abstract:
Objective:To analyze the feasibility of wearable sensor for assessing the severity of tremor in patients with Parkinson disease (PD). Methods:Totally 15 PD subjects and 8 healthy subjects completed the standard action for detecting resting tremor in unified PD rating scale (UPDRS) with the detecting equipment on their hands. The time domain and frequency domain of acceleration signal collected during rest tremor were analyzed, and their correlations with rest tremor score in UPDRS were explored. Results:The logarithm of mean acceleration, root-mean-square roughness, peak amplitude and peak power were well assessed, which were all significantly correlated with rest tremor score in UPDRS (r=0.960,0.961,0.893,0.944). Conclusions:The wearable tremor data acquisition device is accurate, objective and digital in evaluation of resting tremor in PD patients.