Abstract: Objective：To analyze the anesthetic managements during transapical aortic valve implantation and the prognosis of patients. Methods：Totally 11 cases undergoing TATAVI was enrolled (the average age was 77.91), including 7 cases of aortic stenosis and 4 cases of aortic regurgitation. Hydration treatment was started preoperatively, and strict anesthetic design and careful hemodynamic managements were adopted. After induction the temporary pacemaker wire was placed via the internal jugular vein. The hemodynamic parameters, extubation time, length of ICU stay and hospitalization days, complications and allcause mortality before surgery, during surgery and after surgery was recorded and analyzed. Results：The 9 out of 11 patients experienced successful valve implantation procedure, 1 patient suffered hepatic and renal dysfunction in 1 week after surgery, and 2 patients suffered hypoxemia, and one of the two died at last. All the complications occurred in patients with aortic stenosis. Compared with baseline, the patients’ blood pressure, heart rate (HR), cardiac output (CO), and cardiac index (CI) after induction were significantly reduced until the valve opened （P＜0.05）. To the end of the surgery, CO and HR reduced below the basic level, and mean arterial pressure (MAP) and CI were still below the basic level. But the hemodynamics fluctuated in an acceptable range, and did not result in any adverse consequences. Conclusions：Even if the anesthesia of TATAVI is challenging, strict anesthetic design and careful hemodynamic management can ensure the safety of patients. Also the patients with aortic valve stenosis suffered more complicated surgical procedure and unfavorable prognosis.