早期肺癌立体定向放射治疗的临床研究进展

摘要: 立体定向放射治疗（stereotactic body radiotherapy, SBRT）以及立体定向消融放射治疗(stereotactic ablative radiotherapy, SABR)为局部精确放射治疗方法，目前广泛运用于早期不能手术的非小细胞肺癌(nonsmallcell lung cancer, NSCLC)。在部分临床试验中，其3年局部控制率及3年生存率已接近手术治疗的效果，并且对患者的肺功能影响小。本文对早期肺癌精准治疗的临床实践及研究进展作简要综述。

Abstract: Stereotactic body radiotherapy (SBRT) and stereotactic ablative radiotherapy (SABR), methods of high local precision, have been widely used in early stage inoperable nonsmallcell lung cancer (NSCLC) patients. In some clinical trials, the 3year local control rate and 3year survival rate were close to the effect of surgery, and had little effect on the pulmonary function of patients.This paper briefly reviews the clinical practice and research progress of SBRT/SABR in early stage NSCLC.