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大隐静脉改良射频消融术治疗大隐静脉曲张的疗效分析

Analysis of the therapeutic effect of modified radiofrequency ablation on great saphenous vein varicosity

  • 摘要:
    目的 比较大隐静脉改良射频消融术(radiofrequency ablation, RFA)联合硬化剂注射与大隐静脉高位结扎和剥脱术(high stripping and ligation, HSL)联合硬化剂注射治疗大隐静脉曲张的疗效。
    方法 选择南通大学附属医院介入与血管外科组2022年5月至2024年3月收治的220例接受大隐静脉曲张手术的患者(252条患肢),根据手术方式分为RFA组(大隐静脉改良RFA联合硬化剂注射治疗,110例患者125条患肢)和HSL组(HSL联合硬化剂注射治疗,110例患者127条患肢)。比较HSL组和RFA组疗效、手术时间、术中出血量、术后下床活动时间和术后并发症情况。分别通过视觉模拟评分(visual analogue scale, VAS)、静脉临床严重程度评分(venous clinical severity score, VCSS)、慢性静脉功能不全问卷14问(chronic venous insufficiency questionnaire-14 item, CIVIQ-14)评估患者疼痛程度、疾病严重程度及生活质量。
    结果 两组患者治疗总有效率差异无统计学意义,RFA组疗效等级分布优于HSL组(P=0.044)。与HSL组相比,RFA组手术时间缩短、手术切口减少、术中出血量减少、术后更早下床活动(P<0.01),总并发症发生率更低(P=0.006)。RFA组术后1个月VAS、VCSS、CIVIQ-14评分低于HSL组(P<0.01)。术后随访6个月,两组复发率差异无统计学意义。
    结论 与HSL联合硬化剂注射相比,大隐静脉改良RFA联合硬化剂注射治疗大隐静脉曲张具有创伤小、恢复快、并发症少、术后生活质量高等优点,值得临床推广应用。

     

    Abstract:
    Objective To compare the efficacy of modified radiofrequency ablation (RFA) combined with sclerosing agent injection and high stripping and ligation (HSL) combined with sclerosing agent injection in the treatment of great saphenous vein varicosity.
    Methods A total of 220 patients (252 affected limbs) who underwent surgery for great saphenous vein varicosity at Affiliated Hospital of Nantong University from May 2022 to March 2024 were selected. They were divided into RFA group (110 patients and 125 affected limbs treated with modified RFA combined with sclerosing agent injection) and HSL group (110 patients and 127 affected limbs treated with HSL combined with sclerosing agent injection) according to the surgical methods. The treatment effect, surgical time, bleeding during the surgery, time to get out of bed after surgery, and various postoperative complications were compared between the two groups. The pain level, disease severity, and the quality of life were measured using the visual analog scale (VAS), venous clinical severity score (VCSS) and chronic venous insufficiency questionnaire-14 item (CIVIQ-14), respectively.
    Results There was no statistically significant difference in the total effective rate between the two groups of patients, but the distribution of efficacy levels in the RFA group was better than that in the HSL group (P=0.044). Compared with the HSL group, the RFA group had shorter surgery time, fewer incisions during surgery, less bleeding during the surgical process, shorter time to get out of bed after surgery(P<0.01), and a lower overall complication rate (P=0.006). The RFA group had lower postoperative VAS, VCSS, and CIVIQ-14 scores than the HSL group 1 month after surgery (P<0.01). During 6 months of postoperative follow-up, the recurrence rates were similar between the two groups. Conclusions Compared with HSL combined with sclerosing agent injection, the modified RFA combined with sclerosing agent injection for the great saphenous vein varicosity has the advantages of less trauma, faster recovery, fewer complications, better postoperative quality of life, and is worthy of clinical promotion and application.

     

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