Application of Guidezilla extension catheter during percutaneous coronary intervention for non-total occlusive calcified lesions

Objective：To investigate the efficacy and safety of Guidezilla during percutaneous coronary intervention (PCI) for non-total occlusive calcified coronary lesions. Methods：The patients with non-total occlusive calcified coronary lesions were collected between March 2015 and August 2017. All of them received Guidezilla-assisted PCI due to the difficulties of balloon or stent delivering. The demographic data, medical history, lesion characteristics, Guidezilla procedural success rate, PCI success rate, and PCI-related complications were recorded and analyzed.Results：One hundred and eighty-three patients were selected. Almost all of the coronary calcified lesions (99.5%) were classified as type B2/C. Among which, 94.0% were accompanied by multi-vessel diseases and 85.3% coronary tortuosity or angulation. The majority of patients (87.4%) used Guidezilla due to difficulties of delivering stents across the calcified lesions. Guidezilla procedural and PCI success rate was 89.6% and 97.3%, respectively. The incidence of operation-related complications during PCI was 3.3% (6 cases), and among which, 66.7% (4 cases) was coronary dissection. The incidence of major adverse cardiac events (MACEs) was 2.2% (4 cases) and 7.7% (14 cases) during hospitalization and the follow-up period of 12-month, respecitively. Conclusions：Guidezilla-assisted PCI is effective and safe in patients with non-total occlusive and moderate-severe calcified coronary lesions.