Objective To investigate the safety and efficacy of piecemeal cold snare polypectomy (p-CSP) for ≥20 mm large colorectal laterally spreading tumor (LST).
Methods Eligible patients with colorectal LST with large diameter ≥20 mm were prospectively included between November 2021 and June 2022. After submucosal injection of staining agent in the lesion, the snare was used to perform endoscopic p-CSP. The primary outcome was the lesion recurrence within 6 months after p-CSP. The secondary outcome was adverse events (such as bleeding, perforation) happening, etc..
Results A total of 13 patients were included, and the average diameter of the lesions was 2.3 (2-3.3) cm. All tumors were successfully removed by p-CSP with 16.1 (7-31) minutes of average operation time, and the average number of slices was 4.2 (2-7). One case of intraoperative bleeding was successfully managed by metal clips. There was no intraoperative deep injury, delayed bleeding or delayed perforation. All patients received surveillance colonoscopy inspection 6 months after operation, and there was no local recurrence or distant metastasis.
Conclusion p-CSP might be safe and effective for colorectal LST≥20 mm.
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