Objective To assess the systolic function of single left ventricle before and after Glenn procedure by three-dimensional speckle tracking imaging (3DSTI).
Methods Before and after Glenn procedure, the systolic function of the left ventricle was assessed by 3DSTI and cardiac magnetic resonance (CMR) in 17 children with single left ventricle, and compared with 17 age- and gender-matched healthy children (control group).
Results Compared with children in the control group, end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV) of children in the single left ventricle group increased significantly (P < 0.01), ejection fraction (EF), global longitudinal strain (GLS), global circumferential strain (GCS), average tangential strain (TS), average longitudinal strain (LS), average circumferential strain (CS), and average radial strain (RS) were impaired (P < 0.01). After the operation, GCS, CS, and RS were significantly improved (P < 0.05), but EF, GLS, GCS, TS, LS, CS, and RS were still poorer than those in the control group (P < 0.05). GCS was significantly correlated with EF measured by CMR (r=-0.793, P < 0.001).
Conclusion Single left ventricle could be accompanied by impaired ventricular systolic function, which might be partially improved by Glenn procedure, and 3DSTI is an accurate clinical tool for the assessment of ventricular systolic function.
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