Analysis of related factors in risk stratification of acute pulmonary thromboembolism

Objective To investigate the correlation between risk stratification and risk factors in patients with acute pulmonary thromboembolism (APTE).

Methods Totally, 123 patients with suspected pulmonary thromboembolism were selected from May 2019 to may 2020 and divided into embolism group (n=93) and normal control group (n=30). The embolism patients were divided into high/medium risk group (n=60) and low-risk group (n=33), their medical records were collected, and the correlation between APTE risk stratification and the risk factors was analyzed by the multivariate logistic regression model.

Results There were statistical significant differences in the age, incidences of atrial fibrillation, coronary disease, lower extremity venous thrombosis, cerebrovascular disease, and the levels of D-D, FIB and A-aDO₂ among three groups(P < 0.05). In APTE patients, elevated pulmonary artery pressure accounted for the highest proportion (51.22%). Age, coronary disease, cerebrovascular disease, lower extremity venous thrombosis, D-D, FIB, and A-aDO₂ independently affected the risk stratification of APTE (P < 0.05). ROC curve results showed that AUC of age, D-D, FIB, and A-aDO₂ for the diognosis of APTE was 0.621 (95% CI 0.571-0.782), 0.646 (95% CI 0.580-0.792), 0.887 (95% CI 0.815-0.958), and 0.785 (95% CI 0.686-0.885), respectively.

Conclusions Age, coronary disease, cerebrovascular disease, lower extremity venous thrombosis, D-D, FIB, and A-aDO₂ are the influencing factors of risk stratification of APTE. They have a higher value in predicting high/medium risk APTE.