Objective To evaluate the therapeutic effect of combined photoelectric therapy on facial wrinkles using the meta-analysis method.
Methods The literature about combined photoelectric therapy for facial wrinkles was searched in databases including CNKI, Wanfang data, PubMed, and Web of Science, studies that were duplicated, had no control group, or had missing data were excluded. The literature-related bias was evaluated, and the indexes of efficacy for wrinkles were analyzed by Review Manager 5.3 software.
Results A total of 13 studies were included, including 1 181 subjects and 644 in the combined treatment group and 627 in the single treatment group. According to the Meta-analysis, the effect of the combined treatment group was better than that in the single treatment group (OR=2.25, 95%CI 1.69-3.00, P < 0.000 1). In the sensitivity analysis, each study has little impact on the overall meta-analysis.
Conclusions The effect of combined photoelectric therapy for facial wrinkles is often superior to single photoelectric therapy. It is necessary to improve combined photoelectric strategies, establish evaluation criteria, and take further categorical arguments.
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