Tissue tracking magnetic resonance for evaluation of left ventricular global myocardial deformation in healthy subjects

Objective To explore the left ventricular (LV) myocardial deformation function in healthy subjects using cardiac magnetic resonance (CMR) tissue tracking imaging derived LV deformation parameters.

Methods Thirty nine healthy volunteers who underwent CMR imaging in Zhongshan Hospital, Fudan University in 2018 were randomly enrolled. The LV myocardial deformation was evaluated using tissue tracking analysis module of CVI analyzing software based on cine MR sequences. Comparation of LV deformation was done according to level (LV basal, mid and apical planes), layer (subendocardial and subepicardial myocardium), gender, and age groups.

Results LV myocardial systolic deformation function in normal subjects increased from basal plane to apical plane. LV myocardial systolic deformation function decreased from subendocardial myocardium to subepicardial myocardium. Gender had little influence on the LV deformation function.

Conclusion MR-based LV global deformation parameters could be a useful method to assess LV myocardial deformation function.