Diagnostic value of acetic acid chromoendoscopy combined with narrow-band imaging in gastric intestinal metaplasia

Objective To investigate the diagnostic effect and value in acetic acid chromoendoscopy combined with narrow-band imaging mode for gastric intestinal metaplasia (GIM) in Helicobacter pylori positive patients.

Methods Ninety-three patients with Helicobacter pylori infection were examined by endoscopy. They were observed and biopsied by esophagogastroduodenoscopy (EGD) mode, acetic acid chromoendoscopy (ACC) mode, and ACC combined with narrow-band imaging(NBI)mode. The diagnostic effects of the three models for GIM were calculated.

Results The diagnostic sensitivity of ACC combined with NBI mode for GIM was 92.06%, much higher than that of ACC 74.60% and EGD 30.16%. The AUC of three models was 0.584, 0.790 and 0.860 respectively.

Conclusions ACC combined with NBI can significantly improve the diagnosis of GIM, and might be a good tool for GIM screening.