| Clinical characteristics of hospitalized heart failure patients with different ejection fraction in China |
| Received:September 16, 2023 Revised:October 17, 2023 Click here to download the full text |
| Citation of this paper:CUI Xiao-tong,WANG Peng,JIN Xue-juan,ZHOU Jun,XU Ya-mei,MICHAEL Fu,HU Kai,SUN Ai-jun,ZHOU Jing-min,GE Jun-bo.Clinical characteristics of hospitalized heart failure patients with different ejection fraction in China[J].Chinese Journal of Clinical Medicine,2023,30(5):759-762 |
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| Author Name | Affiliation | E-mail | | CUI Xiao-tong | Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Disease, National Center for Clinical Medical Research in Radiology and Therapy, Shanghai 200032, China | | | WANG Peng | Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Disease, National Center for Clinical Medical Research in Radiology and Therapy, Shanghai 200032, China | | | JIN Xue-juan | Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Disease, National Center for Clinical Medical Research in Radiology and Therapy, Shanghai 200032, China | | | ZHOU Jun | Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Disease, National Center for Clinical Medical Research in Radiology and Therapy, Shanghai 200032, China | | | XU Ya-mei | Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Disease, National Center for Clinical Medical Research in Radiology and Therapy, Shanghai 200032, China | | | MICHAEL Fu | Department of Cardiology, Sahlgrenska Hospital Affiliated to University of Gothenburg, Gothenburg 41685, Sweden | | | HU Kai | Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Disease, National Center for Clinical Medical Research in Radiology and Therapy, Shanghai 200032, China | | | SUN Ai-jun | Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Disease, National Center for Clinical Medical Research in Radiology and Therapy, Shanghai 200032, China | sun.aijun@zs-hospital.sh.cn | | ZHOU Jing-min | Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Disease, National Center for Clinical Medical Research in Radiology and Therapy, Shanghai 200032, China | zhou.jingmin@zs-hospital.sh.cn | | GE Jun-bo | Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Disease, National Center for Clinical Medical Research in Radiology and Therapy, Shanghai 200032, China | |
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| Abstract:Objective To investigate the clinical characteristics among three different left ventricular ejection fraction (LVEF) subtypes of patients with chronic heart failure (HF) in China. Methods The data were from China National Heart Failure (CN-HF) registry (NCT02079428). Patients were categorized into three groups based on their LVEF: HF with reduced ejection fraction (≤40%) group (HFrEF group), HF with mildly reduced ejection fraction (41%-49%) group (HFmrEF group), and HF with preserved ejection fraction (≥50%) group (HFpEF group). Basic characteristics in each group were analyzed and compared. Results A total of 5 605 hospitalized patients with HF were enrolled in this real world registry study (mean age was ［69.5±13.5］ years old, 59.9% were male). Compared to HFrEF group (n=2 068), HFpEF group (n=2 941) had more females (48.5% vs 29.1%) and patients were older (［71.1±12.9］ years old vs ［66.9±13.9］ years old), with less New York Heart Assocation (NYHA) Ⅲ-Ⅳ ones (43.3% vs 73.7%) , and more hypertension patients (74.3% vs 64.3%). There were significant difference among the three groups in gender, age, NYHA grade and hypertension rate (P＜0.000 1). The 3-year all-cause mortality rate was 20.7% in all patients, 26.4%, 21.6, and 16.5% in HFrEF, HFmrEF, and HFpEF patients, respectively (Z=8.507 4, P＜0.001). Conclusions Compared with HFrEF patients, HFpEF patients are older, more often women, and have a higher prevalence of comorbidities, and have a relatively favorable prognosis during 3 year follow-up. |
| keywords:heart failure left ventricular ejection fraction clinical characteristics prognosis |
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