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Correlation analysis between coronary slow flow and visceral adiposity index
Received:March 29, 2023  Revised:June 19, 2023  Click here to download the full text
Citation of this paper:YUAN Yan,SHA Xiao-juan,MA Dong-li,JIA Hui-hui.Correlation analysis between coronary slow flow and visceral adiposity index[J].Chinese Journal of Clinical Medicine,2023,30(5):819-824
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Author NameAffiliationE-mail
YUAN Yan Department of Cardiovascular Medicine, Dongying People's Hospital, Dongying 257091, Shandong, China  
SHA Xiao-juan Department of Cardiovascular Medicine, Dongying People's Hospital, Dongying 257091, Shandong, China  
MA Dong-li Department of Internal Medicine, Dongying Dongcheng Community Health Service Center, Dongying 257091, Shandong, China  
JIA Hui-hui Department of Cardiovascular Medicine, Dongying People's Hospital, Dongying 257091, Shandong, China 1175904260@qq.com 
Abstract:Objective To explore the correlation between visceral adiposity index (VAI) and coronary slow flow phenomenon (CSFP), to analyze the pathophysiological characteristics of CSFP. Methods 75 patients who underwent coronary angiography in Dongying People’s Hospital from January 2021 to December 2022 and showed slow flow of epicardial coronary artery without obvious lesions were selected as CSFP group. In addition, 65 patients with normal coronary artery were selected as the normal group. The height, weight, waist circumference (WC) and other general data of the two groups of patients were measured, and blood was collected to detect total cholesterol, low density cholesterol, high density lipoprotein cholesterol (HDL-C), triglyceride (TG), fasting blood glucose and other indicators. Results There were significant differences in body mass index (BMI), ([27.65±2.90] kg/m2 vs [23.99±2.3] kg/m2, P<0.001), WC ([94.25±11.65] cm vs [83.20±5.7] cm, P<0.001), hypertension (66.7% vs 41.5%, P= 0.003), smoking (38.7% vs 12.3%, P<0.001), TG ([2.49±1.04] mmol/L vs [1.48±0.69] mmol/L, P<0.001), HDL-C ([1.18± 0.26] mmol/L vs [1.05±0.22] mmol/L, P=0.003) and Lipoprotein(a) ([498.69±299.87] mmol/L vs [180.54±201.93] mmol/L, P<0.001), VAI ([4.09±1.74] vs [2.66±1.81], P<0.001) between CSFP group and normal group. VAI was strongly correlated with CSFP, with statistical significance (P<0.001). According to the quartile grouping of VAI, the multi-factor logistic regression analysis of the risk of CSFP in adults with different VAI showed that the risk of CSFP in the high VAI group was higher than that in the low VAI group (P<0.05) after adjusting for the proportion of men, WC, BMI, high blood pressure (HBP) positive rate, smoking history positive rate, β2-microglobulin (BMG), TG, HDL-C and other factors. Finally, the ROC curves of VAI predicting the risk of CSFP in subjects of different sexes were drawn respectively. The AUC of male VAI predicting CSFP was 0.848 (95% CI 0.764-0.931), and the cut-off value was 2.369 3. The AUC of female VAI predicting CSFP was 0.866 (95% CI 0.754-0.978), and the cut-off value was 2.525 1. Conclusions There is a strong positive correlation between VAI and the incidence of CSFP in adults. With the increase of VAI, the risk of CSFP also increases; VAI has good predictive value for CSFP.
keywords:coronary slow flow  obesity  visceral adiposity index
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