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The impact of gender on severe diabetic foot endovascular interventions
Received:January 19, 2023  Revised:February 12, 2023  Click here to download the full text
Citation of this paper:LI Da-zhi,ZHU Jiang,YU Qing-yuan,XU Jin-yan,LI Tao,BAO Jun-min,YUAN Liang-xi.The impact of gender on severe diabetic foot endovascular interventions[J].Chinese Journal of Clinical Medicine,2023,30(1):44-48
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Author NameAffiliationE-mail
LI Da-zhi Department of Vascular Surgery, The First Affiliated Hospital of the Naval Medical University, Shanghai 200433, China  
ZHU Jiang Department of Vascular Surgery, The First Affiliated Hospital of the Naval Medical University, Shanghai 200433, China  
YU Qing-yuan Department of Vascular Surgery, The First Affiliated Hospital of the Naval Medical University, Shanghai 200433, China  
XU Jin-yan Department of Vascular Surgery, The First Affiliated Hospital of the Naval Medical University, Shanghai 200433, China  
LI Tao Department of Vascular Surgery, The First Affiliated Hospital of the Naval Medical University, Shanghai 200433, China  
BAO Jun-min Department of Vascular Surgery, The First Affiliated Hospital of the Naval Medical University, Shanghai 200433, China  
YUAN Liang-xi Department of Vascular Surgery, The First Affiliated Hospital of the Naval Medical University, Shanghai 200433, China yuanlx116@163.com 
Abstract:Objective To explore the relationship between gender and the efficacy of endovascular therapy in patients with severe diabetes foot (Wagner grade 3-5). Methods From January 2019 to January 2022, 168 patients with severe diabetes foot who received peripheral endovascular treatment in the First Affiliated Hospital of Naval Military Medical University were included. They were divided into male group (n=118) and female group (n=50) according to gender. To compare the characteristics of lower limb vascular disease, the treatment methods during operation, and collect the data of wound healing rate and amputation after operation. Results In patients with severe diabetes foot, the wound healing of the female group was worse than that of the male group at 3 and 6 months after surgery (P=0.035, P=0.002), but there was no significant difference in the amputation rate between the two groups. Multivariate regression analysis showed that women (OR=5.24, 95%CI 1.227-22.382; P=0.025) and the number of lesions involving the inferior genicular artery (OR=5.24, 95%CI 1.213-14.709; P=0.024) were associated with poor wound healing 6 months after surgery. Among the patients with lesions involving the inferior genicular artery, the wound healing of female patients was poor 6 months after operation (P<0.001). Conclusions The female patients are old at the time of treatment, with complicated complications, and the main complication is infragenual vascular disease, and the condition of intraoperative intervention and postoperative wound healing is poor. Female patients with diabetes foot should receive endovascular treatment earlier and more actively, which has positive significance for improving the prognosis of female patients.
keywords:gender  diabetic foot  endovascular intervention  prognosis
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