Advance on the clinical research of Alzheimer’s treatment |
Received:December 30, 2022 Revised:January 30, 2023 Click here to download the full text |
Citation of this paper:HUANG Qiang,SANG Shao-ming,PAN Xiao-li,ZHONG Chun-jiu.Advance on the clinical research of Alzheimer’s treatment[J].Chinese Journal of Clinical Medicine,2023,30(2):199-208 |
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Author Name | Affiliation | E-mail | HUANG Qiang | Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | SANG Shao-ming | Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | PAN Xiao-li | Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | ZHONG Chun-jiu | Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai 200032, China Institutes of Brain Science, Collaborative Innovation Center for Brain Science, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai 200032, China | zhongcj@163.com |
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Abstract:Alzheimer disease (AD) is one of the most prevalent neurodegenerative diseases, and its high morbidity would lead to heavy disease burden. As the pathogenesis of AD remains unclarified, current therapies could only slow down the disease progression rather than reverse the disease course. For decades, multiple non-drug treatments have been tested in the clinical trials as well as treatments involving novel developed drugs, and the corresponding outcomes have been disclosed. We reviewed the recently finished and on-going clinical trials focusing on AD in this article. |
keywords:Alzheimer disease drug development non-drug treatment |
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