| The effect of peroxisome proliferator-activated receptor γ in placenta on maternal and fetal health: recent progress |
| Received:November 26, 2022 Revised:December 31, 2022 Click here to download the full text |
| Citation of this paper:BAI Fan,ZHANG Jia-ling,GUI Yong-hao.The effect of peroxisome proliferator-activated receptor γ in placenta on maternal and fetal health: recent progress[J].Chinese Journal of Clinical Medicine,2023,30(1):127-136 |
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| Abstract:Peroxisome proliferator-activated receptor γ (PPAR γ) is a nuclear receptor of ligand-dependent transcription factor involved in diverse biological processes including adipocyte differentiation, glucose homeostasis, and immune response. In recent years, a growing number of studies have highlighted the essential role of PPAR γ in the mammalian placenta. This article reviews the recent progress in the research of PPAR γ in the development of placenta, pathological pregnancy and the toxic effects of environmental pollutants on the placenta through PPAR γ, in order to improve the awareness of PPAR γ in the placenta and illuminate the significance of PPAR γ in pregnancy. |
| keywords:peroxisome proliferator-activated receptor γ placenta gestational diabetes mellitus preeclampsia |
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