| Application of different sevoflurane vaporizer initial concentration settings in middle-flow combined intravenous- inhalation anesthesia |
| Received:September 18, 2022 Revised:December 31, 2022 Click here to download the full text |
| Citation of this paper:WANG Hao-ran,WANG Di,CAO Han-zhong,WANG Ling-yan.Application of different sevoflurane vaporizer initial concentration settings in middle-flow combined intravenous- inhalation anesthesia[J].Chinese Journal of Clinical Medicine,2023,30(2):330-334 |
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| Author Name | Affiliation | E-mail | | WANG Hao-ran | Department of Anesthesiology, Tumor Hospital Affiliated to Nantong University, Nantong 226300, Jiangsu, China | | | WANG Di | Department of Anesthesiology, Tumor Hospital Affiliated to Nantong University, Nantong 226300, Jiangsu, China | | | CAO Han-zhong | Department of Anesthesiology, Tumor Hospital Affiliated to Nantong University, Nantong 226300, Jiangsu, China | | | WANG Ling-yan | Department of Anesthesiology, Tumor Hospital Affiliated to Nantong University, Nantong 226300, Jiangsu, China | ntwhrwly@126.com |
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| Abstract:Objective To explore the effects of different initial concentration of sevoflurane vaporizer (Fd) on the “washing” time and anesthetic depth in combined intravenous-inhalation anesthesia. Methods A total of 80 patients who underwent pelvic or abdominal surgery in Tumor Hospital Affiliated to Nantong University from February 2020 to May 2022 were selected and treated with combined intravenous-inhalation anesthesia. According to the different Fd, the patients were randomly divided into high concentration group (group H, n=40) and low concentration group (group L, n=40). After induction of intravenous anesthesia, the sevoflurane vaporizer was opened and the fresh gas flow (FGF) was adjusted to 2 L/min. According to the patient’s age, Fd was adjusted to 3 minimum alveolar concentration (MAC) and 2 MAC, respectively in group H and group L. The BIS, body temperature, mean arterial pressure (MAP), heart rate (HR), vaporizer opening time (T1), time of end-expiratory sevoflurane concentration (CETSev) reaching 0.7 MAC (T2), “washing” time (time from T1 to T2) and regulation times of vaporizer were compared between the two groups. Results The “washing” time in group H was (102.8±8.6) s, which was significantly shorter than that in group L (［198.0±16.4］ s,P＝0.010). There was no significant difference in MAP, HR, body temperature, PETCO2 and BIS between the two groups at T1 and T2 time. There was no significant difference in the regulation times of vaporizer (［3.6±0.3］ times vs ［3.4±0.3］ times) and sevoflurane consumption (11.95 mL/h vs 12.02 mL/h) between the two groups. Conclusions In combined intravenous-inhalation anesthesia, sevoflurane Fd setting of 3 MAC and 2 MAC can reach enough anesthetic depth before the effect of intravenous anesthetic wearing away. To shorten the “washing” time of sevoflurane, vaporizer setting at 3 MAC is a good choice. |
| keywords:sevoflurane combined intravenous-inhalation anesthesia minimum alveolar concentration “washing” time anesthetic depth |
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