| Feasibility of measuring GFR of patients with renal antedisplacement by anterior image processing in renal dynamic imaging |
| Received:April 18, 2022 Revised:May 03, 2023 Click here to download the full text |
| Citation of this paper:YANG Jun-jie,ZHANG Yi-qiu,YU Hao-jun,HE Yi-bo,SHI Hong-cheng.Feasibility of measuring GFR of patients with renal antedisplacement by anterior image processing in renal dynamic imaging[J].Chinese Journal of Clinical Medicine,2023,30(3):468-473 |
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| Author Name | Affiliation | E-mail | | YANG Jun-jie | Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | ZHANG Yi-qiu | Department of Nuclear Medicine, Zhongshan Hospital, Fudan University (Xiamen Branch), Xiamen 361015, Fujian, China
Nuclear Medicine Institute of Fudan University, Shanghai 200032, China
Shanghai Institute of Medical Imaging, Shanghai 200032, China | zhang.yiqiu@zs-hospital.sh.cn | | YU Hao-jun | Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Nuclear Medicine Institute of Fudan University, Shanghai 200032, China
Shanghai Institute of Medical Imaging, Shanghai 200032, China | | | HE Yi-bo | Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Nuclear Medicine Institute of Fudan University, Shanghai 200032, China
Shanghai Institute of Medical Imaging, Shanghai 200032, China | | | SHI Hong-cheng | Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Department of Nuclear Medicine, Zhongshan Hospital, Fudan University (Xiamen Branch), Xiamen 361015, Fujian, China
Nuclear Medicine Institute of Fudan University, Shanghai 200032, China
Shanghai Institute of Medical Imaging, Shanghai 200032, China | |
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Abstract:Objective To explore the feasibility and accuracy of anterior image processing in renal dynamic imaging to determine glomerular filtration rate (GFR) in patients with unilateral renal antedisplacement. Methods A total of 22 patients with unilateral renal antedisplacement who underwent renal dynamic imaging to determine GFR by Gates in the Department of Nuclear Medicine, Zhongshan Hospital, Fudan University from August 2017 to December 2021 were selected. The anterior and posterior image processing were applied simultaneously, posterior images for both kidneys and anterior images for single kidney with antedisplacement. The GFR obtained from the posterior image processing of normal single kidney and the GFR obtained from the anterior image processing of kidney with antedisplacement were added as GFR-optimized; the GFR values of both kidneys obtained from regular posterior image processing were recorded as GFR-regular. The estimated GFR (eGFR) was calculated by the equation based on serum creatinine (sCr) recommended by Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI). The difference among GFR-optimized, GFR-regular and eGFR were compared, and the correlation was evaluated using Pearson analysis. Results The anterior depth of single kidney with antedisplacement was significantly less than the posterior depth ([7.97±1.71] cm vs[13.45±2.86] cm,
P<0.001); the value of GFR obtained by anterior imaging processing of single kidney with antedisplacement was significantly greater than that obtained by posterior imaging processing ([41.43±12.84] mL·min-1·[1.73 m2]-1 vs[31.05±12.79] mL·min-1·[1.73 m2]-1,
P<0.001). Compared with eGFR ([85.46±18.80] mL·min-1·[1.73 m2]-1), GFR-optimized overestimated 1.836 mL·min-1·
(1.73 m2)-1 (95%CI-1.546-5.219, Padjusted=0.815), and there was a high positive correlation between them (r=0.915, P<0.001). Compared with eGFR, GFR-regular underestimated 8.543 mL·min-1·[1.73 m2]-1 (95%CI 2.199-14.886, Padjusted=0.032), and there was a moderate correlation between them (r=0.654, P=0.001). Conclusions For the patients with obvious kidney antedisplacement and the anterior depth of the kidney is less than the posterior depth, the GFR obtained from the anterior image processing in renal dynamic imaging is more accurate than that obtained from regular posterior image processing. |
| keywords:renal dynamic imaging anterior image processing posterior image processing renal antedisplacement glomerular filtration rate |
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