| Exploration of impact factors on set-up errors in IMRT for breast cancer |
| Received:March 23, 2022 Revised:April 19, 2022 Click here to download the full text |
| Citation of this paper:DING Wei-jie,SUN Jing,LIN Gen-lai,MA Gui-fen.Exploration of impact factors on set-up errors in IMRT for breast cancer[J].Chinese Journal of Clinical Medicine,2022,29(3):481-485 |
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| Author Name | Affiliation | E-mail | | DING Wei-jie | Department of Radiation Oncology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | SUN Jing | Department of Radiation Oncology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Department of Radiation Oncology, Xiamen Branch, Zhongshan Hospital, Fudan University, Xiamen 361006, Fujian, China | | | LIN Gen-lai | Department of Radiation Oncology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | MA Gui-fen | Department of Radiation Oncology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | ma.guifen@zs-hospital.sh.cn |
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| Abstract:Objective To explore the factors influencing set-up errors of intensity modulated radiotherapy (IMRT) for breast cancer by image guided technique of cone-beam computed tomography (CBCT). Methods 51 patients with breast cancer who received radiotherapy in the Radiotherapy Department of Zhongshan Hospital, Fudan University from August 2020 to May 2021 were randomly selected, all patients were divided into three groups by surgical procedures, ages and tumour site. Values of set-up errors caused by these factors were compared among these groups in the longitude (X axis), latitude (Y axis) and vertical (Y axis) directions. The relationship between the three factors and set-up errors data were analysed by multiple linear regression analysis. Results No statistical significant were found between groups of surgical procedures in X, Y and Z axis directions. The subgroup analysis was carried out according to the surgical procedures at different ages and different tumour site. It was found that the set-up error in the head-foot direction of the elderly group receiving breast conserving surgery was significantly greater than that of the middle-aged group (P=0.044). No statistical significant was found in the rest of directions for this group. The set-up errors for left-side patients receiving modified radical mastectomy were higher than the right-side ones in Y axis (P=0.008). No statistical significant was found in the rest of directions for this group. Statistical significant relationship was identified between of set-up errors in Y axis direction and tumour site (P=0.024) analyzed by regression analysis. Conclusion Tumour site may increase set-up errors in Y axis direction. It is necessary to reduce the tension of the left breast cancer patients during radiotherapy, while the elderly patients should increase the frequency of image guidance to improve the accuracy of treatment. |
| keywords:cone-beam computed tomography ages breast cancer IMRT set-up error |
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