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Establishment and application of evaluation model of antibiotics use density based on CMI and rank-sum ratio
Received:March 20, 2022  Revised:September 27, 2022  Click here to download the full text
Citation of this paper:CAO Lei,SUN Zhan,DING Fang,SUO Tao,ZHANG Ya-ping,CHENG Zhang-zhang,LI Xiao-yu.Establishment and application of evaluation model of antibiotics use density based on CMI and rank-sum ratio[J].Chinese Journal of Clinical Medicine,2022,29(6):932-938
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Author NameAffiliationE-mail
CAO Lei Department of Medicial, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
SUN Zhan Department of Medicial, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
DING Fang Department of Medicial, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
SUO Tao Department of Medicial, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
ZHANG Ya-ping Department of Medicial, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
CHENG Zhang-zhang Department of Pharmacy, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
LI Xiao-yu Department of Pharmacy, Zhongshan Hospital, Fudan University, Shanghai 200032, China li.xiaoyu@zs-hospital.sh.cn 
Abstract:Objective To achieve refinement management of antibiotics by innovatively introducing relevant key indicators to control antibiotics use density (AUD). Methods Based on the data of case mix index (CMI), the utilization rate of antibiotics in DIP system, and AUD in HIS system in a Class Ⅲ Grade A general hospital in East China from January to June 2021, the introduced key indicators were established and the optimal linear regression model was established. The non-integral rank method was used to rank and calculate. Rank-sum ratio (RSR) grading based on CMI adjusted AUD was compared with RSR grading based on AUD single assessment. Results The RSR classification of AUD of 32 departments in the hospital was studied by introducing CMI values. It was found that the classification results of 12 departments changed, accounting for 37.5%, and the overall number of departments (classified as lower and middle level) in need of strengthening control increased. After the introduction of CMI to adjust AUD, control level raised in 7 departments and fell in 5 departments. Conclusions The grading evaluation model of based on CMI and RSR is effective in the control of AUD in these departments.
keywords:case mix index  rank-sum ratio  grade evaluation model  antibiotics use density
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