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Research progress of effects of mitochondrial dynamics on energy metabolism-related diseases
Received:February 19, 2022  Revised:March 24, 2022  Click here to download the full text
Citation of this paper:ZHOU Yi-le,SHI Yi,FANG Hao,HU Yan.Research progress of effects of mitochondrial dynamics on energy metabolism-related diseases[J].Chinese Journal of Clinical Medicine,2023,30(3):525-533
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Author NameAffiliationE-mail
ZHOU Yi-le Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
SHI Yi Institute of Clinical Science, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
FANG Hao Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China  
HU Yan Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China hu.yan1@zs-hospital.sh.cn 
Abstract:Mitochondria, as the main energy supply organelles in the body, maintain balance mainly through mitochondrial dynamics-fusion and division process and mitochondrial autophagy. The accumulation of dysfunctional mitochondria will lead to cell apoptosis and damage of tissues and organs with high demand for energy metabolism. This review focuses on mitochondrial dynamics and its impact on clinically common energy metabolism-related diseases.
keywords:mitochondrial dynamics  energy metabolism  neurological diseases  diabetes  cardiovascular diseases
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