Research progress of effects of mitochondrial dynamics on energy metabolism-related diseases |
Received:February 19, 2022 Revised:March 24, 2022 Click here to download the full text |
Citation of this paper:ZHOU Yi-le,SHI Yi,FANG Hao,HU Yan.Research progress of effects of mitochondrial dynamics on energy metabolism-related diseases[J].Chinese Journal of Clinical Medicine,2023,30(3):525-533 |
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Author Name | Affiliation | E-mail | ZHOU Yi-le | Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | SHI Yi | Institute of Clinical Science, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | FANG Hao | Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | HU Yan | Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | hu.yan1@zs-hospital.sh.cn |
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Abstract:Mitochondria, as the main energy supply organelles in the body, maintain balance mainly through mitochondrial dynamics-fusion and division process and mitochondrial autophagy. The accumulation of dysfunctional mitochondria will lead to cell apoptosis and damage of tissues and organs with high demand for energy metabolism. This review focuses on mitochondrial dynamics and its impact on clinically common energy metabolism-related diseases. |
keywords:mitochondrial dynamics energy metabolism neurological diseases diabetes cardiovascular diseases |
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