| Progress in diagnosis and treatment of intracranial gliosarcoma |
| Received:November 02, 2021 Revised:April 12, 2022 Click here to download the full text |
| Citation of this paper:XU Jue-feng,XU Rong.Progress in diagnosis and treatment of intracranial gliosarcoma[J].Chinese Journal of Clinical Medicine,2022,29(3):499-503 |
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| Abstract:Gliosarcoma (GSM) is a variant of glioblastoma (GBM), which is the most malignant subtype glioma in the WHO pathological grade (WHO grade Ⅳ). The characteristic of GSM is that its tissue contains two components:glioma and sarcoma. GSM is divided into two subtypes:primary and secondary. GSM is usually treated by total surgical resection, radiotherapy, with or without chemotherapy, but the therapeutic effect is not exact. It is reported that the treatment scheme is similar to that of GBM cases, but with different treatment outcomes. This review summarizes the biological characteristics, imaging findings, treatment and prognosis of GSM cases. |
| keywords:gliosarcoma genomic alternation radiotherapy chemotherapy prognosis |
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