| Clinical features analysis of adenovirus type 7 infection in adults |
| Received:October 11, 2021 Revised:January 10, 2022 Click here to download the full text |
| Citation of this paper:ZHANG Ye-ting,CAI Dong-ping,REN Chuan-lu.Clinical features analysis of adenovirus type 7 infection in adults[J].Chinese Journal of Clinical Medicine,2022,29(5):826-829 |
| Hits: 616 |
| Download times: 212 |
| Author Name | Affiliation | E-mail | | ZHANG Ye-ting | Department of Laboratory, No. 904 Joint Logistical Support Force hospital of PLA, Wuxi 214044, Jiangsu, China | | | CAI Dong-ping | Department of Laboratory, No. 904 Joint Logistical Support Force hospital of PLA, Wuxi 214044, Jiangsu, China | | | REN Chuan-lu | Department of Laboratory, No. 904 Joint Logistical Support Force hospital of PLA, Wuxi 214044, Jiangsu, China | CLU_REN@126.com |
|
| Abstract:Objective To analyze the clinical characteristics and related laboratory indexes changes of patients with human adenovirus-7 (HAdV-7) infection, and the changes of white blood cell, procalcitonin and lymphocyte subpopulations after infection, so as to provide reference for the prevention and control of adenovirus infection and clinical diagnosis and treatment. Methods All the exposed 524 adults were included, the HAdV-7 nucleic acid was detected by reverse transcription polymerase chain reaction and the clinical characteristics, blood routine indexes, procalcitonin and lymphocyte subgroups were statistically analyzed for 30 d. Results A total of 73 infected patients with HAdV-7 were male and 19-33 years old. The main clinical symptoms were fever (100.0%) and pharyngeal pain (68.5%). In the infection group, white blood cell count and PCT increased, and the proportions of total CD3+T cell and CD3+CD4+T cell and the ratio of CD4/CD8 decreased, and the difference was statistically significant (P<0.05). The highest value of WBC was at day 6, the highest value of PCT was at day 3, the total CD3+T cells in the 3rd, 6th and 9th day, the ratios of CD3+CD4+T cells and the CD4/CD8 decreased (P<0.05). Conclusion HAdV-7 infection is onset of acute, the main symptom is fever and sore throat. WBC, PCT and lymphocyte subsets change with the progression of the disease. |
| keywords:adenovirus infection human adenovirus-7 procalcitonin lymphocytes subgroup |
| HTML View Full Text View/Add Comment Download reader |
|
|
|