| Experience of 100 cases of organ donation from organ procurement organization in a third class hospital in East China |
| Received:August 29, 2021 Revised:February 19, 2022 Click here to download the full text |
| Citation of this paper:QI Gui-sheng,DONG Xiao-yan,YE Sheng-hao,PAN Chun-hui,ZHANG Xue-jun,SONG Kang.Experience of 100 cases of organ donation from organ procurement organization in a third class hospital in East China[J].Chinese Journal of Clinical Medicine,2022,29(3):448-453 |
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| Author Name | Affiliation | E-mail | | QI Gui-sheng | Organ Procurement Organization, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Department of Urology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shanghai Key Laboratory of Organ Transplantation, Shanghai 200032, China | | | DONG Xiao-yan | Organ Procurement Organization, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | YE Sheng-hao | Organ Procurement Organization, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | PAN Chun-hui | Organ Procurement Organization, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | ZHANG Xue-jun | Organ Procurement Organization, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | SONG Kang | Organ Procurement Organization, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Department of Liver surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shanghai Key Laboratory of Organ Transplantation, Shanghai 200032, China | song.kang@zs-hospital.sh.cn |
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| Abstract:Objective To review and analyze the 100 DCD cases conducted by the organ procurement organization (OPO) of Zhongshan Hospital, Fudan University. Methods Data of the 100 DCD cases conducted by the OPO of Zhongshan Hospital from July 2014 to March 2021 were retrospectively collected. Medical record included age, gender, primary disease and region. Parameters including potential donation rate, production ratio and utilization rate were also calculated. Results From 2014 to 2021, the annual PMP of our OPO working area were 1.7, 4.1, 4.5,8.6, 5.2, 3.1, and 5.9, respectively. The PMP data were in accordance with the general PMP of Shanghai. Our OPO has successfully conducted donation of 88 livers, 200 kidneys and 6 hearts with a production ratio of 2.94. The utilization rate was 96.6%, 93.5% and 100% for liver, kidney and heart, respectively. The average age of donors was 44.7 years old, with male exceeding female (80% vs 20%). Only 20% of the donors were local resident. The average hospitalization day was 6.1 d. The constituent ratio of the primary disease was 48% for cerebral hemorrhage, 44% for cranial injury, 5% for cerebral infarction and 3% for ischemic hypoxic encephalopathy. 91% of the cases raised from ICU. The donation rate of potential donors was 32% in our cases. Reasons for failed donation included rejection from relatives (70%), inappropriate health condition (21%) and premature death before donation (9%). Conclusions Intrinsic factors, including cerebral hemorrhage and infarction, has exceeded trauma and cranial injury and have become the leading primary disease of the donors. Elder donors are also not rare cases. To increase the donation willingness of the local resident, increase the donation rate of potential donors and elevate the production ratio are the main tasks OPO have to challenge in the future. ICU hospitalized the most donors, therefore ICU doctors and nurses should pay full proactive to identify potential donors and strengthen the ability to maintain organs. |
| keywords:DCD organ procurement organization organ transplantation |
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