| The relationship between early postnatal arterial blood values and moderate and severe bronchopulmonary dysplasia in preterm infants |
| Received:August 13, 2021 Revised:February 08, 2022 Click here to download the full text |
| Citation of this paper:HAN Xiao-ya,ZHAO Yi-wei,MIAO Xiao-lin,CUI Shu-dong.The relationship between early postnatal arterial blood values and moderate and severe bronchopulmonary dysplasia in preterm infants[J].Chinese Journal of Clinical Medicine,2022,29(2):213-217 |
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| Author Name | Affiliation | E-mail | | HAN Xiao-ya | Department of Pediatrics, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu, China | | | ZHAO Yi-wei | Department of Pediatrics, Yueqing Municipal People's Hospital, Yueching 325600, Zhejiang, China | | | MIAO Xiao-lin | Department of Pediatrics, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu, China | | | CUI Shu-dong | Department of Pediatrics, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu, China | csd9758@126.com |
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| Abstract:Objective To study the relationship between arterial blood pH, PaO2, and PaCO2 in the first week after birth and moderate and severe bronchopulmonary dysplasia (BPD) in preterm infants. Methods A cohort of 236 consecutive preterm infants with ＜32 gestational weeks were selected from January of 2017 to December of 2019, 54 infants with moderate and severe BPD were identified as the study group and the other as the control group. Early blood gas values and clinical characteristics were collected and analyzed. Results Compared with the control group, significantly lower pH ([7.25±0.12] vs [7.31±0.09], P＝0.001) of 1st day, lower PaO2 ([63.20±23.75] mmHg vs [75.91±20.70] mmHg, P＜0.001), higher PaCO2 ([43.59±9.87] mmHg vs [38.26±9.11] mmHg, 1 mmHg＝0.133 kPa, P＜0.001) of 7th day occurred in the study group. Lower pH of 1st day and lower PaO2 of 7th day after birth were the independent risk factors of moderate and severe BPD besides lower gestational age, lower birth weight, and mechanical ventilation. Conclusion The early hypoxia and acidosis after birth may affect the progress of moderate and severe BPD. |
| keywords:bronchopulmonary dysplasia blood gas derangement preterm infant risk factor |
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