| Research progress of extracrystalline functions of βB2-crystallin |
| Received:June 05, 2021 Revised:July 22, 2021 Click here to download the full text |
| Citation of this paper:HUANG Wei,LI Mei-hui,LIU Sheng-nan,GU Zhong-yi,ZHANG Jun-jie.Research progress of extracrystalline functions of βB2-crystallin[J].Chinese Journal of Clinical Medicine,2022,29(6):1030-1033 |
| Hits: 801 |
| Download times: 216 |
| Author Name | Affiliation | E-mail | | HUANG Wei | Department of Gynecology and Obstetrics, Changhai Hospital, Naval Medical University, Shanghai 200433, China | | | LI Mei-hui | Department of Gynecology and Obstetrics, Changhai Hospital, Naval Medical University, Shanghai 200433, China | | | LIU Sheng-nan | Department of Gynecology and Obstetrics, Changhai Hospital, Naval Medical University, Shanghai 200433, China | | | GU Zhong-yi | Department of Gynecology and Obstetrics, Changhai Hospital, Naval Medical University, Shanghai 200433, China | | | ZHANG Jun-jie | Department of Gynecology and Obstetrics, Changhai Hospital, Naval Medical University, Shanghai 200433, China | zhangjj910@163.com |
|
| Abstract:βB2-crystallin is the main structural protein in the vertebrate lens. In addition to lens, recent studies have found that βB2-crystallin also plays a very prominent and even unique role outside the lens. βB2-crystallin is unexpectedly highly expressed in retina, brain, testis, and ovary. It can not only promote the regeneration of optic nerve axons, protect the injured optic nerve, but also affect sensory motor gating and hippocampal function, and even plays an important role in reproductive function, or even related to fetal abortion. In addition, new studies have shown that βB2-crystallin is also related to the occurrence and development of a variety of tumors. This paper reviews the function and research progress of βB2-crystallin function outside the lens. |
| keywords:βB2-crystallin retina ovary abortion hippocampus tumor |
| HTML View Full Text View/Add Comment Download reader |
|
|
|