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Retrospective analysis of the influence of different anesthesia methods on mechanical thrombectomy in patients with acute ischemic stroke
Received:May 24, 2021  Revised:August 31, 2021  Click here to download the full text
Citation of this paper:DAI Yuan-qiang,BO Lu-long,BU Lan,NI Li-ya,LIN An-qi,LI Bin-ben.Retrospective analysis of the influence of different anesthesia methods on mechanical thrombectomy in patients with acute ischemic stroke[J].Chinese Journal of Clinical Medicine,2022,29(2):200-205
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Author NameAffiliationE-mail
DAI Yuan-qiang Department of Anesthesiology, The First Affiliated Hospital of Naval Medical University, Shanghai 200433, China  
BO Lu-long Department of Anesthesiology, The First Affiliated Hospital of Naval Medical University, Shanghai 200433, China  
BU Lan Department of Anesthesiology, The First Affiliated Hospital of Naval Medical University, Shanghai 200433, China  
NI Li-ya Department of Anesthesiology, The First Affiliated Hospital of Naval Medical University, Shanghai 200433, China  
LIN An-qi Department of Anesthesiology, The First Affiliated Hospital of Naval Medical University, Shanghai 200433, China  
LI Bin-ben Department of Anesthesiology, The First Affiliated Hospital of Naval Medical University, Shanghai 200433, China libinben@126.com 
Abstract:Objective To explore the short-term prognosis of patients with acute ischemic stroke (AIS) treated with intravascular mechanical thrombolysis under different anesthesia methods and its related risk factors. Methods The AIS patients admitted to our hospital from May 2013 to July 2017 who underwent endovascular mechanical thrombolysis were reviewed. According to the general data and disease status, the patients who underwent general anesthesia were compared with the patients who underwent sedation or local anesthesia with spontaneous breathing retained, and the information related to surgical anesthesia was analyzed. Results The preoperative OCSP classification of stroke patients in the two groups showed different manifestations. The NIHSS score in the general anesthesia group was higher than that in the non-general anesthesia group with a significant statistical difference (P<0.05). The proportion of critical consciousness level in the general anesthesia group was higher than that in the nongeneral anesthesia group (P<0.05); NIHSS score at 2 h (P<0.05) and 24 h (P<0.05) after surgery was still higher in the general anesthesia group than that in the non-general anesthesia group. The time from onset to recanalization (P<0.05) and from puncture to recanalization (P<0.05) in the general anesthesia group was longer than that in the non-general anesthesia group. The duration of anesthesia induction in the general anesthesia group was also significantly longer than that in the non-general anesthesia group (P<0.05).The results showed that higher preoperative NIHSS score was associated with more serious postoperative neurological impairment (OR=1.098, 95%CI 1.037-1.162) and worse postoperative rehabilitation with the increase of age (OR=1.030, 95%CI 1.007-1.053), and it was also found that longer time between puncture and recanalization was associated with more serious postoperative functional damage (OR=1.006, 95%CI 1.001-1.011). Conclusion Preoperative disease severity, age, and the time from puncture to recanalization seriously affect the prognosis of AIS patients, and whether it is related to anesthesia method needs to be further studied.
keywords:anesthesia method  acute ischemic stroke  endovascular mechanical thrombectomy  prognosis  risk factors
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