| Advances in etiology of vulvar lichen sclerosus |
| Received:May 06, 2021 Revised:January 05, 2022 Click here to download the full text |
| Citation of this paper:SUN Xiao-yi,XU Cong-jian,SUI Long,CONG Qing.Advances in etiology of vulvar lichen sclerosus[J].Chinese Journal of Clinical Medicine,2022,29(6):1039-1045 |
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| Author Name | Affiliation | E-mail | | SUN Xiao-yi | Clinical Medical School of Shanghai Medical College, Fudan University, Shanghai 200032, China | | | XU Cong-jian | Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China | | | SUI Long | Medical Center of Diagnosis and Treatment for Cervical Disease, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China | | | CONG Qing | Medical Center of Diagnosis and Treatment for Cervical Disease, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China | qingcong@fudan.edu.cn |
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| Abstract:Vulvar lichen sclerosus is a chronic nonneoplastic skin disease, which can occur in women at any age. The main clinical manifestactions of this disease include pruritus and pain of vulva, atrophy and whitening of skin and mucosa, atrophy and disappearance of labia minora. The risk of vulvar cancer increased significantly in these patients. The etiology is still unclear. Potential pathogenic factors of vulvar lichen sclerosus include autoimmunity, genetic factors, sex hormone influence, infection factors, oxidative stress, and so on. This paper summarizes the advances in etiology of vulvar lichen sclerosus. |
| keywords:vulvar lichen sclerosus etiology autoimmunity oxidative stress |
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