| Pathological anlysis of lymphadenopathy in patients with acquired immunodeficiency syndrome accompanied by interventional ultrasound |
| Received:March 17, 2021 Revised:July 16, 2021 Click here to download the full text |
| Citation of this paper:LIU Jian-jian,HUANG Jing-jing,ZHANG Hui,MA Xin,FENG Yan-ling,WU Dou,SHI Xia,LU Qing.Pathological anlysis of lymphadenopathy in patients with acquired immunodeficiency syndrome accompanied by interventional ultrasound[J].Chinese Journal of Clinical Medicine,2021,28(5):818-822 |
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| Author Name | Affiliation | E-mail | | LIU Jian-jian | Department of Ultrasound, Shanghai Public Health Clinical Center, Shanghai 201508, China | | | HUANG Jing-jing | Department of Ultrasound, Shanghai Public Health Clinical Center, Shanghai 201508, China | | | ZHANG Hui | Department of Ultrasound, Shanghai Public Health Clinical Center, Shanghai 201508, China
Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai 200032, China | zhanghui1958@hotmail.com | | MA Xin | Department of Ultrasound, Shanghai Public Health Clinical Center, Shanghai 201508, China | | | FENG Yan-ling | Department of Pathology, Shanghai Public Health Clinical Center, Shanghai 201508, China | | | WU Dou | Department of Ultrasound, Shanghai Public Health Clinical Center, Shanghai 201508, China | | | SHI Xia | Department of Ultrasound, Shanghai Public Health Clinical Center, Shanghai 201508, China | | | LU Qing | Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai 200032, China | |
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| Abstract:Objective: To explore the diagnostic value of ultrasound-guided needle biopsy in acquired immunodeficiency syndrome (AIDS) accompanied with lymphadenopathy. Methods: From Apr. 2017 to Dec. 2020, 130 patients with AIDS accompanied with lymphadenopathy underwent ultrasound-guided needle biopsy in the Shanghai Public Health Clinical Center. The clinical data and pathological diagnosis were retrospectively analyzed,and the diagnostic value of ultrasound-guided needle biopsy for etiologies of lymphadenopathy was analyzed. Results: Among the 130 patients, 82 (63.1%) and 36 (27.7%) cases were diagnosed as benign lesions and malignant ones, respectively. The pathological types of benign lesions were as follows:56 lymphatic tuberculosis, 7 non-tuberculous mycobacteria infections, 6 marneffei infections, 5 necrotizing lymphadenites, 2 cryptococcus infections, 2 cytomegalovirus infections,1 staphylococcus aureus,1 lymphoid tissue hyperplasia, 1 lymphocyst, and 1 Epstein-Barr virus infection. The pathological types of the malignant lesions were as follows:17 lymphomas (5 diffuse large B-cell lymphomas, 5 Burkitt lymphomas, 1 plasmablastic lymphoma, 1 small lymphocytic lymphoma, 1 anaplastic large cell lymphoma, and 4 unclassified lymphomas), 17 metastatic malignant tumors, and 2 Kaposi sarcoma, and 12 were undefined (11 patients were considered as benign lesions and 1 case was considered as tumor necrosis). Therefore, the diagnostic rate of ultrasound-guided needle biopsy for lymphadenopathy in AIDS patients reached 90.8%, and no complications occurred. Conclusions: Ultrasound-guided needle biopsy has a high diagnostic rate in pathological types of lymphadenopathy in patients with AIDS. It is safe, minimally invasive, and of great value in the early diagnosis and precise treatment for lymphadenopathy in patients with AIDS, and is worthy of clinical application. |
| keywords:intervention ultrasound acquired immunodeficiency syndrome lymph node diagnosis |
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