| Diagnosis and treatment strategy for refractory focal epilepsy in multidisciplinary model |
| Received:February 02, 2021 Revised:March 31, 2021 Click here to download the full text |
| Citation of this paper:CAI Yang,LUO Rong-kui,HU Fan,LIN Jiang,SHI Hong-cheng,JI Yuan,DING Jing,WANG Xin.Diagnosis and treatment strategy for refractory focal epilepsy in multidisciplinary model[J].Chinese Journal of Clinical Medicine,2021,28(2):299-304 |
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| Author Name | Affiliation | E-mail | | CAI Yang | Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | LUO Rong-kui | Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | HU Fan | Department of Neurosurgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | LIN Jiang | Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | SHI Hong-cheng | Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | JI Yuan | Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | DING Jing | Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | | | WANG Xin | Department of Neurology, Zhongshan Hospital, Fudan University, Shanghai 200032, China | wang.xin@zs-hospital.sh.cn |
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| Abstract:Objective: To explore the diagnosis and treatment strategy of multidisciplinary team (MDT) for refractory focal epilepsy.Methods: The patient was diagnosed with intractable temporal lobe epilepsy. The interictal scalp electroencephalogram showed unsynchronized epileptiform discharges on bilateral temporal lobes. The conventional magnetic resonance imaging was normal with no obvious lesions. Then the epileptogenic focus and treatment method were comfirmed by MDT diagnosis and presurgical evaluation.Results: The patient was diagnosed with right medial temporal lobe epilepsy after detailed preoperative assessment, and was further operated on the anterior right temporal lobe, hippocampus, and amygdaloid nucleus. The postoperative pathology revealed the ganglioglioma with the focal cortical dysplasia in surrounding tissues. There was no seizure more than one year after operation. Conclusions: The MDT system could help to precisely localize the epileptogenic focus and provide a foundation for the surgical resection range. The MDT diagnosis and treatment could help the patient to reach postoperatively seizure-free. |
| keywords:refractory epilepsy magnetic resonance imaging position emission computed tomography stereo-electroencephalography multidisciplinary team |
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