| Fibroblast growth factor-10 in prevention and treatment of respiratory diseases |
| Received:February 01, 2021 Revised:April 27, 2021 Click here to download the full text |
| Citation of this paper:SONG Juan,HOU Dong-ni,TONG Lin,SONG Yuan-lin.Fibroblast growth factor-10 in prevention and treatment of respiratory diseases[J].Chinese Journal of Clinical Medicine,2021,28(3):335-341 |
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| Author Name | Affiliation | E-mail | | SONG Juan | Department of Respiratory and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shanghai Respiratory Research Institute, Shanghai 200032, China
Institute of Respiratory Diseases, Fudan University, Shanghai 200032, China | | | HOU Dong-ni | Department of Respiratory and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shanghai Respiratory Research Institute, Shanghai 200032, China
Institute of Respiratory Diseases, Fudan University, Shanghai 200032, China | | | TONG Lin | Department of Respiratory and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shanghai Respiratory Research Institute, Shanghai 200032, China
Institute of Respiratory Diseases, Fudan University, Shanghai 200032, China | tong.lin@zs-hospital.sh.cn | | SONG Yuan-lin | Department of Respiratory and Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Shanghai Respiratory Research Institute, Shanghai 200032, China
Institute of Respiratory Diseases, Fudan University, Shanghai 200032, China | song.yuanlin@zs-hospital.sh.cn |
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| Abstract:Fibroblast growth factor-10 (FGF-10) regulates cell proliferation, migration, differentiation, apoptosis, and participates in the occurrence of various lung diseases. FGF-10 can promote injury repair, inhibit fibrosis, and promote lung mesenchymal stem cell proliferation and mobilization. FGF-10 has protective effects on acute lung injury and airway damage caused by various stimuli. Therefore, local administration of recombinant FGF-10 protein into the lung may become a new strategy for the treatment of certain respiratory diseases. This paper reviews the value and potential prospects of application of FGF-10 in prevention and treatment of respiratory diseases. |
| keywords:fibroblast growth factor-10 acute respiratory distress syndrome lung-resident mesenchymal stem cell respiratory diseases |
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