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Long-term evaluation of left ventricular systolic function in patients with coronary artery disease after percutaneous coronary intervention by layer-specific strain
Received:November 08, 2020  Revised:March 23, 2021  Click here to download the full text
Citation of this paper:GU Shu-lian,WU Wei-hua,XIE Xiao-yi,CHEN Lu,GUO Li-na,MA Lan.Long-term evaluation of left ventricular systolic function in patients with coronary artery disease after percutaneous coronary intervention by layer-specific strain[J].Chinese Journal of Clinical Medicine,2021,28(3):497-501
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Author NameAffiliationE-mail
GU Shu-lian Department of Ultrasound, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China  
WU Wei-hua Department of Ultrasound, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China  
XIE Xiao-yi Department of Ultrasound, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China  
CHEN Lu Department of Ultrasound, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China  
GUO Li-na Department of Ultrasound, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China  
MA Lan Department of Ultrasound, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China malan1994@sina.com 
Abstract:Objective: To evaluate the long-term left ventricular systolic function in patients with coronary artery disease (CAD) witout abnormal wall motion after percutaneous coronary intervention (PCI) by layer-specific strain (LSS). Methods: From March 2017 to January 2018, 54 patients with CAD and PCI operation at the same time in Shanghai Chest Hospital were prospectively included (PCI group), and 46 cases with normal coronary artery angiography constituted the control group. Echocardiography was performed before operation and (21.04±2.27) months after PCI. Layer-specific strain was performed in three apical views to provide global longitudinal peak systolic strains (GLS) in the endocardium, mid-myocardium, and epicardium (GLSendo, GLSmid, and GLSepi). The difference between GLSendo and GLSepi (ΔGLS) was calculated. Results: Patients in the preoperative PCI group had significantly lower GLS compared with those in the control group (all P<0.05). After (21.04±2.27) months of follow-up, GLSendo, GLSmid, and GLSepi in the PCI group were significantly higher than those in the preoperative PCI group (all P<0.05), but still lower than those in the control group (all P<0.05). Among the three groups, ΔGLS was the lowest in the preoperative PCI group (P<0.05), and the ΔGLS in the postoperative PCI group was significantly higher than that in the preoperative PCI group (P<0.05). Conclusions: The GLS of left ventricle is significantly improved after PCI, and the recovery of GLSendo is better than GLSepi. LSS can sensitively and accurately evaluate the long-term changes of left ventricular systolic function in patients with CAD without abnormal wall motion after PCI.
keywords:two-dimensional speckle tracking imaging  layer-specific strain  coronary artery disease  percutaneous coronary intervention  left ventricular systolic function
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