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Quality assessment and evidence-based interpretation of clinical practice guidelines on liver elastography in the diagnosis of hepatic fibrosis using AGREE Ⅱ
Received:September 29, 2020  Revised:October 19, 2020  Click here to download the full text
Citation of this paper:CHEN Jie,NAKAYAMA Kiyoko,CHENG Guang-wen,DING Hong,CHEN Shi-yao.Quality assessment and evidence-based interpretation of clinical practice guidelines on liver elastography in the diagnosis of hepatic fibrosis using AGREE Ⅱ[J].Chinese Journal of Clinical Medicine,2021,28(3):455-459
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Author NameAffiliationE-mail
CHEN Jie Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Evidence-Based Medicine Center of Fudan University, Shanghai 200032, China 
 
NAKAYAMA Kiyoko Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Evidence-Based Medicine Center of Fudan University, Shanghai 200032, China 
 
CHENG Guang-wen Department of Ultrasound, Huashan Hospital, Fudan University, Shanghai 200031, China  
DING Hong Department of Ultrasound, Huashan Hospital, Fudan University, Shanghai 200031, China  
CHEN Shi-yao Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Evidence-Based Medicine Center of Fudan University, Shanghai 200032, China 
chen.shiyao@zs-hospital.sh.cn 
Abstract:Objective: To evaluate the published practice guidelines on non-invasive diagnosis of hepatic fibrosis using liver elastography, and interpret the assessment from the perspective of evidence-based methodology.Methods: The related data were collected by two researchers based on the Chinese and English databases until September 1, 2020. The methodological quality of included guidelines was evaluated by 3 reviewers using the AGREE Ⅱ.Results: A total of 9 guidelines were included. The intraclass correlation coefficient of the three researchers was 0.84±0.43, indicating that the overall consistency was good. The median scores of the six domains in AGREE Ⅱ were 78%, 30%, 33%, 81%, 42% and 47%, respectively.Conclusions: The quality of the existing guidelines is uneven, and there are deficiencies in the personnel involved, formulation rigorousness, applicability, and independence of the guidelines. The evidence-based method should be adopted for revisions based on more high-quality clinical research evidences.
keywords:liver elastography  guideline  consensus  AGREE Ⅱ
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